| Pair Name | Pterostilbene, 3-methyladenine | ||
| Phytochemical Name | Pterostilbene (PubChem CID: 5281727 ) | ||
| Anticancer drug Name | 3-methyladenine (PubChem CID: 135398661 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Pterostilbene, 3-methyladenine | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Biological Phenomena | Induction-->Autophagy | |||
| Gene Regulation | Down-regulation | Expression | VIM | hsa7431 |
| In Vitro Model | MDA-MB-231 | Breast adenocarcinoma | Homo sapiens (Human) | CVCL_0062 |
| BT-549 | Invasive breast carcinoma | Homo sapiens (Human) | CVCL_1092 | |
| Result | These data showed that Fas signaling and autophagy accelerated the aggressiveness of TNBC. Inhibition of autophagy or Fas signaling may provide novel targets for TNBC therapy. | |||
| No. | Title | Href |
|---|---|---|
| 1 | The anti-tumor efficiency of pterostilbene is promoted with a combined treatment of Fas signaling or autophagy inhibitors in triple negative breast cancer cells. Food Funct. 2014 Aug;5(8):1856-65. doi: 10.1039/c4fo00145a. | Click |
